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KMID : 0829220100340050299
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Korean Journal of Oral and Maxillofacial Pathology
2010 Volume.34 No. 5 p.299 ~ p.302
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A Case Report of Precursor T-cell Leukemia/lymphoma Accompanying Mental Nerve Invasion without Recurrence for Central Nervous System
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Han Seon-Hui
Nam Jung-woo
Park Hyok
Kim Hyung-Jun
Kim Nam-Hee
Kim Hyun-Sil
Yook Jong-In
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Abstract
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Facial numbness restricted to the distribution of the mental nerve(mental neuropathy) is called "numb chin syndrome". The clinical importance of this syndrome is associated with first recognition of involvement of malignant diseases. The malignant neoplasm with numb chin syndrome show rapid progression and high mortality. We present a 43-year-old female who had been treated by radiotherapy for precursor T-cell leukemia/lymphoma involving the central nervous system(CNS) previously and later developed mental nerve invasion without central nervous system recurrence. MRI images revealed the CNS tumor mass remitted, and there was no identified peripheral nervous system(PNS) involvement including the mental nerve invasion, nevertheless the patient complained of consistent numbness and pain on right mandibular area. This is the first case of precursor T-cell leukemia/lymphoma accompanying mental nerve invasion without recurrence for central nervous system. Proper interpretation for mental neuropathy may lead to the prompt diagnosis and therapeutic intervention.
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KEYWORD
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Precursor T-cell leukemia/lymphoma, Central nervous system (CNS), Invasion, Mental neuropathy, Numb chin syndrome
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